My research interests are improving our understanding and diagnosis of gynecological conditions.
Paths of Research
Microscopic examination of surgically resected tissue specimens and samples (biopsies) can lead to new understandings of diseases. In addition, novel technologies open new pathways for the investigation of gynecologic disease. The exploration of these new pathways often requires collaboration among colleagues to form a multidisciplinary team. Our areas of interest have included biomarker development for endometrial cancer and recognition of pre-cancerous abnormalities in familial ovarian cancer. (see publications)
The practice of pathology and laboratory medicine is being transformed by rapid biotechnology advances. Although these advances offer new opportunities to improve pathologic diagnosis their adoption must be done within the resource constraints of modern healthcare. Colleagues and I have successfully implemented automated cytology screening for Pap tests and molecular diagnosis of placental molar disease. The use of digital whole slide images for referral and review of pathology cases (WSIRRs) has the potential to improve patient care.(see publications)
Pathologists take the initiative to improve the practice of pathology. Professional involvement is a major opportunity to initiate such improvements. I have served as: a member of the College of American Pathologists’ (CAP) Cytopathology Resource Committee, Chair of a Working Group for the Lower Anogenital Squamous Terminology project of the CAP and American Society of Colposcopy & Cervical Pathology, co-author of the international collaboration on the reporting of endometrial cancer, and contributor to the World Health Organization’s Classification of Tumours Female Reproductive Organs, 4th and 5th editions. (see publications)